Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 6/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874707 | 1.00 | STAT3 (0.34) | STAT3GSK3BBACE1METTL3RORC | |
| SCHEMBL9873918 | 0.85 | GSK3B (0.38) | STAT3GSK3BMETTL3RORCPIM1 | |
| SCHEMBL9873914 | 0.85 | GSK3B (0.38) | STAT3GSK3BMETTL3RORCPIM1 | |
| SCHEMBL9871406 | 0.71 | KDM4E (0.44) | STAT3GSK3BKDM4EKMT2A | |
| SCHEMBL9873589 | 0.71 | KDM4E (0.62) | GSK3BKDM4EKMT2A | |
| SCHEMBL9873858 | 0.70 | RORC (0.42) | RORC | |
| SCHEMBL9873439 | 0.66 | STAT3 (0.43) | STAT3RORCPIM1KDM4EKMT2A | |
| SCHEMBL9874569 | 0.65 | RORC (0.41) | RORCKDM4EKMT2A | |
| SCHEMBL9787964 | 0.64 | IKBKB (0.60) | AURKAPIM1 | |
| SCHEMBL9873617 | 0.64 | KDM4E (0.53) | STAT3GSK3BKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |