Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9871258 | 0.78 | MTOR (0.38) | POLBMTORRAB9ATSHR | |
| SCHEMBL9873432 | 0.77 | POLB (0.35) | NFKB1NFKB2RELAPOLBMEN1 | |
| SCHEMBL9873451 | 0.71 | MTOR (0.37) | POLBMEN1KMT2AMTORRAB9A | |
| SCHEMBL9874781 | 0.71 | MTOR (0.38) | MTORRAB9ATSHR | |
| SCHEMBL9873755 | 0.69 | MTOR (0.42) | POLBMTORRAB9ATSHR | |
| SCHEMBL9871944 | 0.68 | ACACB (0.36) | — | |
| SCHEMBL13945279 | 0.66 | MAOB (0.32) | MEN1KMT2A | |
| SCHEMBL2001481 | 0.65 | TSHR (0.52) | POLBKMT2AMTORRAB9ATSHR | |
| SCHEMBL27213906 | 0.64 | CA12 (0.47) | KMT2ATSHR | |
| SCHEMBL12407025 | 0.64 | MRGPRX4 (0.47) | POLBMEN1KMT2ACPB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990508-A | Reduced side effects | TOYAMA CHEMICAL CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |