Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.64 |
| ▸ | ACHE | P22303 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844210 | 0.88 | ACHE (0.55) | BCHEACHE | |
| SCHEMBL8984077 | 0.88 | KMT2A (0.67) | BCHEACHEKDM4EMEN1HTT | |
| SCHEMBL10845669 | 0.87 | ACHE (0.48) | BCHEACHEMEN1KMT2A | |
| SCHEMBL10846020 | 0.87 | ACHE (0.54) | BCHEACHEMEN1KMT2A | |
| SCHEMBL9875611 | 0.86 | BCHE (0.53) | BCHEACHEKDM4E | |
| SCHEMBL10845120 | 0.84 | ACHE (0.53) | BCHEACHEKDM4E | |
| SCHEMBL9874867 | 0.83 | PABPC1 (0.71) | BCHEACHEKMT2A | |
| SCHEMBL12043396 | 0.82 | BCHE (0.92) | BCHEACHEKDM4EMEN1HTT | |
| SCHEMBL9874160 | 0.81 | BCHE (0.54) | BCHEACHE | |
| SCHEMBL9874141 | 0.81 | BCHE (0.54) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631286-A | MEMORY ENHANCERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-12-23 | — | — | US | claimed |
| EP-2681554-B1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON DICKINSON CO (US) | 2017-08-09 | — | — | EP | disclosed |
| US-9459187-B2 | Blood collection device containing lysophospholipase inhibitor | BECTON, DICKINSON AND COMPANY (US) | 2016-10-04 | — | — | US | disclosed |
| CN-104244902-A | Sample collection devices with blood stabilizing agents | BECTON DICKINSON CO | 2014-12-24 | — | — | CN | disclosed |
| US-20140030754-A1 | BLOOD COLLECTION DEVICE CONTAINING LYSOPHOSPHOLIPASE INHIBITOR | BECTON, DICKINSON AND COMPANY (US) | 2014-01-30 | — | — | US | disclosed |
| US-20130209985-A1 | SAMPLE COLLECTION DEVICES WITH BLOOD STABILIZING AGENTS | BECTON, DICKINSON AND COMPANY | 2013-08-15 | — | — | US | disclosed |
| EP-0179383-B1 | 9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1-OL AND RELATED COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4839364-A | ALZHEIMER*S DISEASE; CHOLINESTERASE INHIBITORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4835275-A | Method of preparing 9-amino-1,2,3,4,-tetrahydroacridin-1-ones and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1989-05-30 | — | — | US | disclosed |
| US-4754050-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4695573-A | COGNITION ACTIVATORS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-09-22 | — | — | US | disclosed |
| US-4631286-A | MEMORY ENHANCERS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0179383-A2 | 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-04-30 | — | — | EP | disclosed |