Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876051 | 0.73 | CYP19A1 (0.40) | CYP19A1MAPTHSP90AA1KMT2A | |
| SCHEMBL9875571 | 0.72 | POLB (0.37) | CYP19A1KMT2A | |
| SCHEMBL9527392 | 0.66 | TRPM8 (0.36) | PPARGMAPTKMT2A | |
| SCHEMBL23863130 | 0.65 | PKM (0.33) | — | |
| SCHEMBL7734404 | 0.64 | — | — | |
| SCHEMBL10730302 | 0.63 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL13887438 | 0.62 | — | — | |
| SCHEMBL12261482 | 0.62 | TRPM8 (0.38) | MAPT | |
| SCHEMBL2310984 | 0.61 | — | — | |
| SCHEMBL23966742 | 0.61 | TRPM8 (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0241232-B1 | ISOXAZOLYLETHANOL DERIVATIVES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-02-27 | — | — | EP | disclosed |