Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876002 | 0.86 | LMNA (0.44) | METAP2CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL29660606 | 0.84 | METAP2 (0.54) | METAP2CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL321962 | 0.84 | METAP2 (0.54) | METAP2CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL9875363 | 0.82 | F2 (0.45) | CYP3A4ALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL9876096 | 0.81 | AR (0.40) | CYP3A4ALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL9875902 | 0.80 | ESR1 (0.49) | CYP3A4ALDH1A1LMNAMAPTCYP1A2 | |
| SCHEMBL9876007 | 0.80 | ESR1 (0.42) | CYP3A4ALDH1A1LMNAMAPTCYP1A2 | |
| Phenazine SCHEMBL29069909 | 0.76 | MAPT (0.46) | METAP2ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL22470160 | 0.69 | PIM1 (0.46) | METAP2CYP3A4ALDH1A1LMNANPSR1 | |
| SCHEMBL21560825 | 0.68 | PIM1 (0.46) | METAP2CYP3A4ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045433-A | Photopolymerization initiators | HITACHI CHEMICAL CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |