Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875737 | 0.95 | NAAA (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9639601 | 0.86 | NAAA (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9639106 | 0.86 | NAAA (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL9516190 | 0.80 | LMNA (0.32) | ALDH1A1LMNA | |
| SCHEMBL10726179 | 0.79 | ALDH1A1 (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL19529573 | 0.78 | RECQL (0.50) | ALDH1A1MAPK1L3MBTL1LMNATSHR | |
| SCHEMBL9639099 | 0.77 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1NPSR1MAPTMAPK1 | |
| SCHEMBL11547557 | 0.77 | NPSR1 (0.48) | ALDH1A1NPSR1MAPTMAPK1L3MBTL1 | |
| SCHEMBL9874906 | 0.77 | MAPT (0.34) | NPSR1MAPTMAPK1L3MBTL1LMNA | |
| SCHEMBL9639155 | 0.75 | NAAA (0.38) | SMN1; SMN2ALDH1A1NPSR1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055584-A | Antiwear agents, antioxidants | R. T. VANDERBILT COMPANY, INC. | 1991-10-08 | — | — | US | disclosed |
| EP-0289964-A1 | Maleic acid derivatives of 2,5-dimercapto-1,3,4-thiadiazoles and lubricating compositions containing same | R.T. VANDERBILT COMPANY, INC. (US) | 1988-11-09 | — | — | EP | disclosed |