Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9516190 | 0.96 | LMNA (0.32) | LMNAHTT | |
| SCHEMBL9875737 | 0.81 | NAAA (0.44) | MAPTNPSR1MAPK1RAD52L3MBTL1 | |
| SCHEMBL9875718 | 0.77 | RAB9A (0.41) | MAPTNPSR1LMNAMAPK1L3MBTL1 | |
| SCHEMBL9639106 | 0.74 | NAAA (0.39) | MAPTNPSR1MAPK1RAD52MEN1 | |
| SCHEMBL9639601 | 0.74 | NAAA (0.39) | MAPTNPSR1MAPK1RAD52MEN1 | |
| SCHEMBL9639099 | 0.67 | ALDH1A1 (0.51) | MAPTNPSR1HTTMAPK1KDM4E | |
| SCHEMBL9639155 | 0.65 | NAAA (0.38) | MAPTNPSR1LMNAMAPK1RAD52 | |
| SCHEMBL16411258 | 0.62 | ALDH1A1 (0.55) | MAPTNPSR1MAPK1RAD52KDM4E | |
| SCHEMBL12611017 | 0.60 | NAAA (0.51) | MAPTNPSR1MAPK1RAD52L3MBTL1 | |
| SCHEMBL10809555 | 0.60 | NAAA (0.51) | MAPTNPSR1MAPK1RAD52L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055584-A | Antiwear agents, antioxidants | R. T. VANDERBILT COMPANY, INC. | 1991-10-08 | — | — | US | disclosed |
| EP-0289964-A1 | Maleic acid derivatives of 2,5-dimercapto-1,3,4-thiadiazoles and lubricating compositions containing same | R.T. VANDERBILT COMPANY, INC. (US) | 1988-11-09 | — | — | EP | disclosed |