Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ATP4A | P20648 | 2/20 | 0.39 |
| ▸ | ATP4B | P51164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9766687 | 0.97 | L3MBTL1 (0.38) | CASP3SENP8SENP7SENP6ATP4A | |
| SCHEMBL9161261 | 0.93 | MEN1 (0.43) | LMNASMN1; SMN2MEN1USP2ALDH1A1 | |
| SCHEMBL9158863 | 0.90 | LMNA (0.46) | LMNASMN1; SMN2HTTL3MBTL1ALDH1A1 | |
| SCHEMBL9159089 | 0.90 | PKM (0.43) | LMNASMN1; SMN2L3MBTL1MEN1USP2 | |
| SCHEMBL9152820 | 0.89 | CYP3A4 (0.44) | LMNASMN1; SMN2L3MBTL1MEN1USP2 | |
| SCHEMBL9158993 | 0.87 | ACACB (0.44) | LMNASMN1; SMN2HTTL3MBTL1MEN1 | |
| SCHEMBL9155906 | 0.87 | CYP2D6 (0.47) | LMNASMN1; SMN2L3MBTL1MEN1USP2 | |
| SCHEMBL9155931 | 0.85 | TAAR1 (0.44) | L3MBTL1ALDH1A1 | |
| SCHEMBL9766609 | 0.83 | ACACB (0.41) | LMNASMN1; SMN2HTTL3MBTL1MEN1 | |
| SCHEMBL9158851 | 0.80 | NQO1 (0.42) | LMNASMN1; SMN2TSHRL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004248-A1 | PYRIDINE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-04-04 | — | — | WO | disclosed |