Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158993 | 0.96 | ACACB (0.44) | ACACBACACAL3MBTL1LMNARAB9A | |
| SCHEMBL9155765 | 0.94 | RAB9A (0.40) | L3MBTL1LMNARAB9AMAPTGAA | |
| SCHEMBL9158863 | 0.92 | LMNA (0.46) | ACACBACACAL3MBTL1LMNARAB9A | |
| SCHEMBL9155906 | 0.91 | CYP2D6 (0.47) | L3MBTL1LMNARAB9AMAPTHSD17B10 | |
| SCHEMBL9158851 | 0.90 | NQO1 (0.42) | L3MBTL1LMNARAB9AMAPTDHFR | |
| SCHEMBL9152820 | 0.89 | CYP3A4 (0.44) | L3MBTL1LMNARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL9766687 | 0.88 | L3MBTL1 (0.38) | L3MBTL1LMNARAB9AMAPTHTT | |
| SCHEMBL9159089 | 0.87 | PKM (0.43) | L3MBTL1LMNASMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL9161261 | 0.85 | MEN1 (0.43) | LMNASMN1; SMN2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL9875889 | 0.83 | CASP3 (0.40) | L3MBTL1LMNAHSD17B10HTTDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |