SCHEMBL987595

SCHEMBL987595

CCCCCOC(=O)CCC(=O)CN

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.96
NAAA Q02083 1/20 0.55
DGKA P23743 1/20 0.55
PRSS1 P07477 1/20 0.51
PRSS2 P07478 1/20 0.51
PRSS3 P35030 1/20 0.51
FAAH O00519 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
THRB P10828 1/20 0.46
CNR1 P21554 1/20 0.46
DNM1 Q05193 1/20 0.46
EPHX1 P07099 1/20 0.43
EPHX2 P34913 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3822217 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
SCHEMBL3829077 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
Hexaminolevulinate SCHEMBL1070663 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
SCHEMBL3824698 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
SCHEMBL3819717 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
SCHEMBL3822297 0.98 HTR2C (1.00) HTR2CNAAADGKAPRSS1PRSS2
Hydrochloric Acid SCHEMBL1613827 0.96 HTR2C (0.97) HTR2CNAAADGKAPRSS1PRSS2
Hexaminolevulinate SCHEMBL937621 0.96 HTR2C (0.97) HTR2CNAAADGKAPRSS1PRSS2
Hydrochloric Acid SCHEMBL1613756 0.96 HTR2C (0.97) HTR2CNAAADGKAPRSS1PRSS2
SCHEMBL987461 0.94 HTR2C (0.86) HTR2CNAAADGKAPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2272538-B1 METHOD OF DETECTING BLADDER CANCER SBI PHARMACEUTICALS CO LTD (JP) 2020-09-02 EP claimed
CN-104524576-A Use of aminolevulinic acid and derivatives thereof PHOTOCURE ASA 2015-04-22 CN claimed
CN-101896203-A Use of solid forms of 5-aminolevulinic acid and derivatives in photodynamic therapy and diagnosis PHOTOCURE ASA 2010-11-24 CN claimed
CN-101631541-A Application of aminolevulinic acid and derivatives thereof PHOTOCURE ASA 2010-01-20 CN claimed
EP-1467706-B1 DERMAL APPLICATION SYSTEM FOR AMINOLEVULINIC ACID-DERIVATIVES PHOTONAMIC GMBH & CO KG (DE) 2007-03-14 EP claimed
US-20060018956-A1 Dermal application system for aminolevulinic acid-derivatives PHOTONAMIC GMBH & CO. KG (DE) 2006-01-26 US claimed
EP-4548917-A1 NON-AQUEOUS PREPARATION WITH EXCELLENT STABILITY Kiyan Pharma Co., Ltd. (JP) 2025-05-07 EP disclosed
CN-119874643-A Paclitaxel prodrug, and preparation method and application thereof 中国药科大学 2025-04-25 CN disclosed
CN-119365191-A Nonaqueous formulations with excellent stability 基扬制药有限公司 2025-01-24 CN disclosed
US-20240299588-A1 NERVE LABEL UCL Business Ltd, University College London (GB) 2024-09-12 US disclosed
EP-4370166-A1 NERVE LABEL UCL Business Ltd (GB) 2024-05-22 EP disclosed
WO-2024005178-A1 NON-AQUEOUS PREPARATION WITH EXCELLENT STABILITY ネオファーマジャパン株式会社 2024-01-04 WO disclosed
WO-2023106413-A1 STABILIZED 5-AMINOLEVULINIC ACID COMPOSITION ネオファーマジャパン株式会社 2023-06-15 WO disclosed
US-20090176881-A1 Unsaturated Alkyl Esters of 5-Aminolevulinic Acid, their Preparation and their Use INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY (KR) 2009-07-09 US disclosed
EP-2055188-A1 POLYPHENOL-CONTENT-INCREASING AGENT FOR PLANT COSMO OIL CO., LTD. (JP) 2009-05-06 EP disclosed
US-7135162-B2 Agent for diagnosing and treating malignant tumors COSMO RESEARCH INSTITUTE (JP) 2006-11-14 US disclosed
US-20060018956-A1 Dermal application system for aminolevulinic acid-derivatives PHOTONAMIC GMBH & CO. KG (DE) 2006-01-26 US disclosed
US-6905671-B1 Diagnostic agents and remedies for malignant tumors COSMO RESEARCH INSTITUTE (JP) 2005-06-14 US disclosed
US-20030065029-A1 Agent for diagnosing and treating malignant tumors COSMO RESEARCH INSTITUTE, COSMO OIL CO., LTD. 2003-04-03 US disclosed
EP-0995448-A1 DIAGNOSTIC AGENTS AND REMEDIES FOR MALIGNANT TUMORS Cosmo Research Institute (JP) 2000-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240299588-A1 NERVE LABEL GAP43, NT5M, NT5E HTR2C 2314/4885NAAA 378/4885DGKA 4456/4885
US-20090176881-A1 Unsaturated Alkyl Esters of 5-Aminolevulinic Acid, their Preparation and their Use ALAD, ALOX5, SLC7A1 HTR2C 1116/4885NAAA 2033/4885DGKA 2663/4885
US-20030065029-A1 Agent for diagnosing and treating malignant tumors ALAD, VHL, AADAT HTR2C 2838/4885NAAA 180/4885DGKA 4509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.