Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 2/20 | 0.38 |
| ▸ | USP7 | Q93009 | 2/20 | 0.38 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876158 | 0.80 | LMNA (0.42) | LMNAKDM4EMAPTTDP1ALPL | |
| SCHEMBL9876169 | 0.78 | LMNA (0.43) | LMNAALPLHSP90AA1HSP90AB1MCOLN3 | |
| SCHEMBL9875589 | 0.78 | HPGD (0.39) | LMNAKDM4EMAPTTDP1USP8 | |
| SCHEMBL9876901 | 0.77 | LMNA (0.42) | LMNAKDM4EALPLHPGDMEN1 | |
| SCHEMBL9875655 | 0.76 | LMNA (0.41) | LMNAKDM4EMAPTTDP1USP8 | |
| SCHEMBL9876172 | 0.76 | LMNA (0.39) | LMNAKDM4EMAPTALPLHPGD | |
| SCHEMBL9521448 | 0.76 | TSHR (0.46) | LMNAKDM4ETDP1HPGDMEN1 | |
| SCHEMBL9876168 | 0.73 | — | — | |
| SCHEMBL9876039 | 0.73 | CCNB2 (0.32) | LMNAMAPTKMT2ANPSR1 | |
| SCHEMBL9876077 | 0.73 | LMNA (0.36) | LMNAKDM4EMAPTALPLHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |