Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 6/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876169 | 0.90 | LMNA (0.43) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL9876158 | 0.78 | LMNA (0.42) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL9523406 | 0.77 | TSHR (0.44) | ALDH1A1KDM4EHPGDNPSR1MEN1 | |
| SCHEMBL9876241 | 0.77 | LMNA (0.41) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL9876172 | 0.76 | LMNA (0.39) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL9876077 | 0.71 | LMNA (0.36) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL9876018 | 0.70 | ALPL (0.41) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL10725033 | 0.69 | SMN1; SMN2 (0.40) | LMNAALDH1A1MCOLN3KDM4EHPGD | |
| SCHEMBL9876056 | 0.69 | — | — | |
| SCHEMBL7591843 | 0.62 | LMNA (0.53) | LMNAALPLHSP90AA1HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |