SCHEMBL9876039

SCHEMBL9876039

CN(C)S(=O)(=O)n1cc(C(=O)c2c(Cl)cc(Cl)cc2Cl)nc1C#N

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CCNB2 O95067 2/20 0.32
CCNE2 O96020 2/20 0.32
CDK1 P06493 2/20 0.32
CCNB1 P14635 2/20 0.32
CCNE1 P24864 2/20 0.32
CDK2 P24941 2/20 0.32
CCNB3 Q8WWL7 2/20 0.32
CDK4 P11802 1/20 0.31
CCND1 P24385 1/20 0.31
KMT2A Q03164 1/20 0.30
GPR35 Q9HC97 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876168 0.79
SCHEMBL9876241 0.73 LMNA (0.41) KMT2ALMNAMAPTNPSR1
SCHEMBL9875374 0.72 HTT (0.33) CCNB2CCNE2CDK1CCNB1CCNE1
SCHEMBL9736209 0.69 KDM4E (0.31) KMT2A
SCHEMBL9734425 0.68 SORD (0.33)
SCHEMBL9521448 0.64 TSHR (0.46) KMT2ALMNAHTTNPSR1
SCHEMBL9077201 0.64 KDM4E (0.40) KMT2AMAPT
SCHEMBL9733639 0.64 SORD (0.30)
SCHEMBL9875589 0.63 HPGD (0.39) KMT2ALMNAMAPTNPSR1
SCHEMBL9845735 0.62 GAA (0.40) KMT2ALMNAMAPTHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5045557-A Imidazable fungicides and use thereof SCHERING AGROCHEMICALS LTD. (GB) 1991-09-03 US disclosed
EP-0284277-A1 Cyanoimidazole fungicides AgrEvo UK Limited (GB) 1988-09-28 EP disclosed