Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL7333919 | 0.94 | KDM4E (0.49) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL7303201 | 0.76 | CXCR6 (0.55) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL7334925 | 0.74 | KDM1A (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7303197 | 0.74 | OPRM1 (0.41) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL7383321 | 0.74 | HTR3A (0.51) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL7363375 | 0.73 | CHRNA7 (0.50) | HTR3AHTR3EHTR3BCHRNB2CHRNA3 | |
| SCHEMBL7387366 | 0.71 | HTR3A (0.68) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL7387363 | 0.71 | HTR3A (0.68) | HTR3AHTR3ESLC22A2HTR3BCHRNB2 | |
| SCHEMBL2343924 | 0.70 | MCL1 (0.57) | — | |
| SCHEMBL29255654 | 0.70 | MCL1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013733-A | Psychological disorders, antianxiety, 5-hydroxytryptamine antagonists | GLAXO GROUP LIMITED (GB) | 1991-05-07 | — | — | US | disclosed |