Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385370 | 0.89 | LMNA (0.60) | LMNACES2CES1NOTUMMAPT | |
| Ammonia Solution, Strong SCHEMBL27316369 | 0.88 | LMNA (0.59) | LMNACES2CES1NOTUMMAPT | |
| SCHEMBL69268 | 0.86 | PTPN11 (0.69) | PTPN11MAPTCA1CA2TDP1 | |
| SCHEMBL29893239 | 0.85 | CFTR (0.50) | PTPN11LMNANOTUMMAPTCFTR | |
| SCHEMBL13063663 | 0.84 | LMNA (0.56) | LMNACES2CES1NOTUMMAPT | |
| SCHEMBL2271347 | 0.84 | LMNA (0.56) | LMNACES2CES1NOTUMMAPT | |
| SCHEMBL22096409 | 0.84 | CA12 (0.50) | PTPN11LMNANOTUMCA1CA2 | |
| SCHEMBL31710343 | 0.84 | CFTR (0.56) | PTPN11LMNANOTUMMAPTCFTR | |
| SCHEMBL31575935 | 0.83 | SRD5A2 (0.65) | LMNACES2CES1NOTUMMAPT | |
| Methylene Chloride SCHEMBL28147089 | 0.83 | LMNA (0.55) | LMNACES2CES1NOTUMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407955-A1 | New hetrazepines acting as PAF antagonists, process for their production and their use as drugs | BOEHRINGER INGELHEIM KG (DE) | 1991-01-16 | — | — | EP | disclosed |