Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7048877 | 0.88 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7048882 | 0.88 | KDM4E (0.41) | KDM4E | |
| SCHEMBL7693611 | 0.88 | KDM4E (0.41) | KDM4E | |
| SCHEMBL482265 | 0.87 | ABCC9 (0.49) | ALDH1A1ABCC9TDP1 | |
| SCHEMBL4715927 | 0.87 | ABCC9 (0.49) | ALDH1A1ABCC9TDP1 | |
| SCHEMBL482263 | 0.87 | ABCC9 (0.49) | ALDH1A1ABCC9TDP1 | |
| SCHEMBL11394655 | 0.85 | ALOX5 (0.45) | ABCC9ALOX5 | |
| SCHEMBL11394662 | 0.85 | ALOX5 (0.45) | ABCC9ALOX5 | |
| SCHEMBL9742155 | 0.85 | KCNA5 (0.40) | ALDH1A1ABCC9ALOX5GAA | |
| SCHEMBL10956358 | 0.85 | ALOX5 (0.45) | ABCC9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071871-A | Pharmaceutically useful benzo(β)pyranes and pyranopyridines | SANDOZ LTD. (CH) | 1991-12-10 | — | — | US | disclosed |