Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879907 | 0.86 | SRC (0.48) | TP53PTGER1TSHRMAPK1HSD17B10 | |
| SCHEMBL29930901 | 0.86 | CCNA2 (0.53) | CCNA2CDK2MAOBTSHRMAPK1 | |
| SCHEMBL9234476 | 0.83 | TNK2 (0.44) | CCNA2CDK2PTGER1ALDH1A1LMNA | |
| SCHEMBL30879866 | 0.83 | ALDH1A1 (0.47) | TP53MAOBHSD17B10MAPTDYRK1A | |
| SCHEMBL9876890 | 0.82 | PTGER1 (0.50) | CCNA2CDK2PTGER1TSHRMAPK1 | |
| SCHEMBL9876523 | 0.81 | PTGER1 (0.39) | CCNA2CDK2PTGER1TSHRMAPK1 | |
| SCHEMBL9877014 | 0.81 | PTGER1 (0.41) | CCNA2CDK2TP53MAOBPTGER1 | |
| SCHEMBL9876520 | 0.80 | PTGER1 (0.38) | CCNA2CDK2PTGER1TSHRMAPK1 | |
| SCHEMBL7359895 | 0.78 | PDE4A (0.53) | TP53TSHRMAPK1HSD17B10MAPT | |
| SCHEMBL9876738 | 0.78 | TP53 (0.54) | CCNA2CDK2TP53MAOBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| EP-0338087-A1 | FUSED PYRAZOLE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR MEDICINAL USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1989-10-25 | — | — | EP | disclosed |