Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL4322061 | 0.92 | ALDH1A1 (0.36) | ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL6520578 | 0.91 | ALDH1A1 (0.55) | ALDH1A1TSHRMAPK1 | |
| Isopropyl Alcohol SCHEMBL9024795 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRLMNA | |
| Chloromethane SCHEMBL11103401 | 0.86 | — | — | |
| SCHEMBL10940023 | 0.85 | — | — | |
| SCHEMBL7240952 | 0.85 | — | — | |
| SCHEMBL1296 | 0.85 | — | — | |
| SCHEMBL1331944 | 0.85 | — | — | |
| Chloroform SCHEMBL7162033 | 0.83 | TSHR (0.38) | ALDH1A1TSHRMAPK1 | |
| Acetic Acid SCHEMBL8834833 | 0.80 | FFAR3 (0.41) | ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102603797-A | Phosphine imide ligand (E)-(2-(diphenyl phosphino) benzylidene) hydrazine as well as synthetic method and application of phosphine imide ligand (E)-(2-(diphenyl phosphino) benzylidene) hydrazine | UNIV NANKAI | 2012-07-25 | — | — | CN | claimed |
| EP-0225130-B1 | LIPOSOME COMPOSITION | Takeda Chemical Industries, Ltd. (JP) | 1991-10-30 | — | — | EP | claimed |
| US-4844904-A | Liposome composition | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-04 | — | — | US | claimed |
| CN-116375734-A | Ballon Sha Weizhi isomer and preparation method thereof | 思科(深圳)药物研发有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-106232587-B | Disubstituted 1,2, 4-triazine compounds | 田边三菱制药株式会社 | 2021-04-13 | — | — | CN | disclosed |
| US-20210093640-A1 | Polycyclic Carbamoylpyridone Derivatives, Pharmaceutical Compositions and Use Thereof | ANDIKANG (WUXI) BIOLOGICAL TECHNOLOGY CO. LTD. (CN) | 2021-04-01 | — | — | US | disclosed |
| EP-3778608-A1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | Andikang (Wuxi) Biological Technology Co., Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |
| US-20190276407-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2019-09-12 | — | — | US | disclosed |
| US-10329263-B2 | Disubstituted 1, 2, 4-triazine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-06-25 | — | — | US | disclosed |
| EP-3473616-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Wakunaga Pharmaceutical Co., Ltd. (JP) | 2019-04-24 | — | — | EP | disclosed |
| CN-107099347-B | A kind of ether diesel oil of clean and environmental protection and preparation method thereof | 孟宪富 | 2019-03-29 | — | — | CN | disclosed |
| US-4336368-A | 4 Deoxy-4-methylene oleandomycin and derivatives thereof | PFIZER INC. (US) | 1982-06-22 | — | — | US | disclosed |
| EP-0051381-A1 | O-sulfated beta-lactam hydroxamic acids | E.R. Squibb & Sons, Inc. (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4283340-A | VITAMINS | PFIZER INC. (US) | 1981-08-11 | — | — | US | disclosed |
| EP-0000243-B1 | PROCESS FOR PREPARING 3,5:4,6- PROTECTED DERIVATIVES OF L- OR D- GULONIC ACID, THEIR USE IN PREPARING 2- KETO-L- OR D- GULONIC ACID OR THEIR ESTERS OR L- OR D- ASCORBIC ACID, AND CERTAIN NOVEL 2-NITRATO-GULONATE INTERMEDIATES | PFIZER INC. (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4228167-A | Diuretic and vasodilating tricyclic quinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-14 | — | — | US | disclosed |
| EP-0000243-A1 | Process for preparing 3,5:4,6- protected derivatives of L- or D- gulonic acid, their use in preparing 2- keto-L- or D- gulonic acid or their esters or L- or D- ascorbic acid, and certain novel 2-nitrato-gulonate intermediates | PFIZER INC. (US) | 1979-01-10 | — | — | EP | disclosed |
| US-4052436-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4051129-A | REACTION OF BENZYLIDENIMINO GROUP WITH HYDRAZINE, AMIDATION | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | disclosed |
| US-3989841-A | ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329263-B2 | Disubstituted 1, 2, 4-triazine compound | NR3C2, REN, NR5A1 | ALDH1A1 68/4885TSHR 759/4885LMNA 2988/4885 |
| US-20190276407-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | CTR9, PYCR1, ACAD9 | ALDH1A1 960/4885TSHR 234/4885LMNA 1870/4885 |
| US-20210093640-A1 | Polycyclic Carbamoylpyridone Derivatives, Pharmaceutical Compositions and Use Thereof | RNGTT, HDAC5, ENTPD5 | ALDH1A1 1462/4885TSHR 4238/4885LMNA 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.