Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9234490 | 0.92 | GSK3B (0.50) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9876891 | 0.88 | LSS (0.44) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9876682 | 0.87 | GSK3B (0.43) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9230726 | 0.87 | GSK3B (0.42) | LSSGSK3BHRH3PTPN1KDM4E | |
| SCHEMBL9876697 | 0.85 | LSS (0.43) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9234584 | 0.85 | LSS (0.46) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9236664 | 0.85 | KDM4E (0.43) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9877732 | 0.85 | ALDH1A1 (0.53) | LSSGSK3BKDRTGFBR1ACVR1 | |
| SCHEMBL9876908 | 0.85 | ALDH1A1 (0.51) | LSSGSK3BHRH3KDM4EALDH1A1 | |
| SCHEMBL9224007 | 0.84 | LSS (0.44) | LSSGSK3BKDRTGFBR1ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006520-A | Antibiotics, antitumor agents, treatment of blood disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-04-09 | — | — | US | disclosed |