Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877820 | 0.91 | NAAA (0.43) | SLC18A2 | |
| SCHEMBL9877016 | 0.91 | SLC18A3 (0.41) | — | |
| SCHEMBL9879730 | 0.87 | FFAR1 (0.49) | — | |
| SCHEMBL9877336 | 0.83 | HCRTR1 (0.45) | — | |
| SCHEMBL9707392 | 0.81 | SLC18A2 (0.38) | SLC18A2 | |
| SCHEMBL11031319 | 0.77 | SLC18A2 (0.42) | SLC18A2 | |
| SCHEMBL9331285 | 0.75 | MFN2 (0.41) | — | |
| SCHEMBL9328954 | 0.73 | HSD17B2 (0.40) | — | |
| SCHEMBL9328964 | 0.73 | HSD17B2 (0.40) | — | |
| SCHEMBL9328959 | 0.73 | HSD17B2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036157-A | Hydroxamic acid derivatives, lipoxygenase and cyclooxygenase inhibitors, anticoagulants, antiinflammatory agents | BURROUGHS WELLCOME CO. | 1991-07-30 | — | — | US | disclosed |
| US-4977188-A | Hydroamic acid derivatives | BURROUGHS WELLCOME CO. (US) | 1990-12-11 | — | — | US | disclosed |
| WO-1990001929-A1 | NEW MEDICAL USE | THE WELLCOME FOUNDATION LIMITED (GB) | 1990-03-08 | — | — | WO | disclosed |
| US-4738986-A | CYCLOOXYGENASE, LIDOXYGENASE INHIBITORS | BURROUGHS WELLCOME CO. (US) | 1988-04-19 | — | — | US | disclosed |
| EP-0196184-A2 | Aryl derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-10-01 | — | — | EP | disclosed |