Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114452 | 0.81 | MEN1 (0.42) | SLC18A2 | |
| SCHEMBL9876918 | 0.77 | SLC18A2 (0.49) | SLC18A2 | |
| SCHEMBL18114396 | 0.76 | OPRM1 (0.41) | — | |
| SCHEMBL18114380 | 0.74 | SIGMAR1 (0.47) | — | |
| SCHEMBL18114384 | 0.73 | MEN1 (0.42) | — | |
| SCHEMBL18114387 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL1914402 | 0.71 | GSK3A (0.43) | — | |
| SCHEMBL2025086 | 0.71 | GSK3A (0.43) | — | |
| SCHEMBL1190776 | 0.70 | CA1 (0.48) | — | |
| SCHEMBL1191156 | 0.70 | CA1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0086678-B1 | PROCESS FOR THE PREPARATION OF 2-ACYL-1,3,4,6,7,11B-2H-HEXAHYDRO-4-PYRAZINO(2,1-A)ISOQUINOLINONES AND INTERMEDIATES | ELF SANOFI (FR) | 1985-07-03 | — | — | EP | disclosed |
| EP-0086678-A1 | Process for the preparation of 2-acyl-1,3,4,6,7,11b-2H-hexahydro-4-pyrazino(2,1-a)isoquinolinones and intermediates | ELF SANOFI (FR) | 1983-08-24 | — | — | EP | disclosed |