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SCHEMBL9876987

SCHEMBL9876987

C[C@H]1CN(C(=O)O)CC[C@]1(O)c1cccc(F)c1

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 9/20 0.48
▸ OPRK1 P41145 9/20 0.48
▸ OPRM1 P35372 6/20 0.45
▸ OPRL1 P41146 3/20 0.45
▸ MC4R P32245 6/20 0.44
▸ MC5R P33032 3/20 0.43
▸ MC3R P41968 1/20 0.43
▸ KCNH2 Q12809 1/20 0.42
▸ CCR2 P41597 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876994 1.00 OPRD1 (0.48) OPRD1OPRK1OPRM1OPRL1MC4R
SCHEMBL9876991 1.00 OPRD1 (0.48) OPRD1OPRK1OPRM1OPRL1MC4R
SCHEMBL18038731 0.85 OPRL1 (0.59) OPRD1OPRK1OPRM1OPRL1
SCHEMBL9312223 0.85 LMNA (0.50) OPRD1OPRK1OPRM1MC4RMC5R
SCHEMBL9312231 0.85 LMNA (0.50) OPRD1OPRK1OPRM1MC4RMC5R
SCHEMBL9312229 0.85 LMNA (0.50) OPRD1OPRK1OPRM1MC4RMC5R
SCHEMBL16423480 0.84 KMT2A (0.51) OPRD1OPRK1OPRM1OPRL1MC4R
SCHEMBL2579926 0.78 OPRD1 (0.48) OPRD1OPRK1OPRM1
SCHEMBL3441859 0.77 OPRM1 (0.60) OPRD1OPRK1OPRM1OPRL1MC4R
SCHEMBL3024931 0.76 KMT2A (0.51) OPRD1OPRK1OPRM1OPRL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0156433-B1 ANTI-VIRALLY ACTIVE PYRIDAZINAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1991-02-27 — — EP disclosed