Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27656366 | 0.83 | P2RX7 (0.50) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL668153 | 0.75 | P2RX7 (0.53) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL28972091 | 0.74 | CA1 (0.42) | P2RX7CA1CA2CA9ALDH1A1 | |
| SCHEMBL2467646 | 0.74 | P2RX7 (0.56) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL18190399 | 0.73 | P2RX7 (0.50) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL16054667 | 0.73 | TAS1R3 (0.52) | P2RX7CTSDALDH1A1HPGDKDM4E | |
| SCHEMBL17063932 | 0.73 | P2RX7 (0.50) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL19409437 | 0.73 | P2RX7 (0.50) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL7599930 | 0.72 | ALDH1A1 (0.52) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL16755442 | 0.72 | CA1 (0.70) | P2RX7CTSDCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |