Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
| ▸ | CTSD | P07339 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877291 | 0.83 | P2RX7 (0.45) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL3135538 | 0.82 | CTSD (0.56) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL14761398 | 0.81 | CTSD (0.47) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL1334610 | 0.81 | PARP1 (0.47) | CLCN2ALDH1A1GABRA1GABRB2MAPT | |
| SCHEMBL1892417 | 0.81 | GABRA1 (0.45) | CLCN2ALDH1A1GABRA1GABRB2HTT | |
| SCHEMBL668153 | 0.81 | P2RX7 (0.53) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL28708772 | 0.80 | GABRA1 (0.48) | CLCN2ALDH1A1GABRA1GABRB2HTT | |
| SCHEMBL27807211 | 0.80 | TAS1R3 (0.47) | P2RX7CTSDCA1CA2CA9 | |
| SCHEMBL28244196 | 0.80 | HPGD (0.60) | ALDH1A1HTTHPGDKDM4EHSD17B10 | |
| SCHEMBL2467646 | 0.79 | P2RX7 (0.56) | P2RX7CTSDCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1964622-B | Mutant receptors and their use in nuclear receptor-based inducible gene expression systems | INTREXON CORP. (US) | 2015-08-26 | — | — | CN | disclosed |
| CN-1964622-A | Mutant receptors and their use in nuclear receptor-based inducible gene expression systems | RHEOGENE INC (US) | 2007-05-16 | — | — | CN | disclosed |