Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | RECQL | P46063 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9180723 | 0.85 | L3MBTL1 (0.43) | ALDH1A1RECQLCYP3A4TSHRTHRB | |
| SCHEMBL9877649 | 0.80 | L3MBTL1 (0.35) | ALDH1A1RECQLCYP3A4TSHRTHRB | |
| SCHEMBL9877591 | 0.78 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRTHRBALOX15 | |
| SCHEMBL9350920 | 0.78 | RAPGEF4 (0.42) | ALDH1A1RECQLCYP3A4TSHRTHRB | |
| SCHEMBL9878782 | 0.77 | RAPGEF4 (0.41) | ALDH1A1RECQLCYP3A4TSHRTHRB | |
| SCHEMBL11207535 | 0.77 | GAA (0.54) | GAAHTR6NSD2 | |
| SCHEMBL9877653 | 0.76 | CPN1 (0.34) | ALDH1A1RECQLL3MBTL1RAPGEF4TDP1 | |
| SCHEMBL9179609 | 0.74 | CYP3A4 (0.37) | ALDH1A1CYP3A4TSHRALOX15HSD17B10 | |
| SCHEMBL13689956 | 0.74 | ALDH1A1 (0.40) | ALDH1A1RECQLCYP3A4TSHRTHRB | |
| SCHEMBL115254 | 0.74 | ALDH1A1 (0.55) | ALDH1A1RECQLCYP3A4TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |