Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | CASP6 | P55212 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878549 | 0.78 | GAA (0.39) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9877382 | 0.76 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9877651 | 0.75 | CA2 (0.43) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9877649 | 0.74 | L3MBTL1 (0.35) | CPN1CPB2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9180723 | 0.73 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9350920 | 0.70 | RAPGEF4 (0.42) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL9878782 | 0.69 | RAPGEF4 (0.41) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL6427620 | 0.69 | RAPGEF4 (0.50) | L3MBTL1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL7528294 | 0.69 | PRKCI (0.39) | ALDH1A1KDM4EPOLBGAAMAPT | |
| SCHEMBL9853650 | 0.69 | RAPGEF4 (0.38) | L3MBTL1ALDH1A1KDM4EPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |