Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 3/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675701 | 0.75 | HRH3 (0.40) | HRH3SIGMAR1AOC2MAOAMAOB | |
| SCHEMBL2452704 | 0.72 | HRH3 (0.37) | HRH3AOC2MAOAMAOB | |
| SCHEMBL8405409 | 0.72 | HRH3 (0.37) | HRH3HTR1ASIGMAR1AOC2MAOA | |
| SCHEMBL502587 | 0.72 | MAOA (0.40) | HRH3AOC2MAOAMAOB | |
| SCHEMBL27574307 | 0.72 | HRH3 (0.37) | HRH3SIGMAR1AOC2MAOAMAOB | |
| SCHEMBL3767763 | 0.72 | HRH3 (0.37) | HRH3SIGMAR1AOC2MAOAMAOB | |
| SCHEMBL18493846 | 0.70 | HRH3 (0.36) | HRH3SIGMAR1AOC2MAOAMAOB | |
| SCHEMBL11451572 | 0.70 | HTT (0.38) | HRH3ALDH1A1 | |
| SCHEMBL2449240 | 0.69 | MAOA (0.37) | HRH3AOC2MAOAMAOB | |
| SCHEMBL6174120 | 0.68 | HRH3 (0.35) | HRH3AOC2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429535-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990002122-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |