Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878330 | 0.83 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KMT2ALMNAKDM4E | |
| SCHEMBL9878469 | 0.81 | KMT2A (0.42) | CD274ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL8164756 | 0.80 | CA2 (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL10891503 | 0.78 | CA1 (0.53) | ALDH1A1KMT2AKDM4EMAPTCA12 | |
| SCHEMBL9878790 | 0.78 | CA2 (0.41) | ALDH1A1KMT2AMEN1NSD2KDM4E | |
| SCHEMBL9879136 | 0.78 | CYP19A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL17774677 | 0.77 | CA2 (0.40) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 | |
| SCHEMBL10389511 | 0.77 | CYP2D6 (0.42) | ALDH1A1KMT2AMEN1NSD2KDM4E | |
| SCHEMBL10902226 | 0.76 | KMT2A (0.53) | ALDH1A1KMT2AMAPTPOLBPKM | |
| SCHEMBL17774706 | 0.76 | RECQL (0.45) | ALDH1A1SMN1; SMN2KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |