Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878396 | 0.83 | CD274 (0.43) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL9878326 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL29597632 | 0.82 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL9877922 | 0.82 | KMT2A (0.58) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL9877899 | 0.80 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL9878203 | 0.79 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL26640646 | 0.78 | MAPT (0.66) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL15546620 | 0.78 | PKM (0.66) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL2307734 | 0.78 | MAPT (0.66) | ALDH1A1SMN1; SMN2MAPTPKMPOLB | |
| SCHEMBL9879074 | 0.77 | HTT (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |