Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9878514 | 0.81 | SIGMAR1 (0.56) | HTR2ASIGMAR1RAB9ASMN1; SMN2MMP1 | |
| SCHEMBL9063683 | 0.79 | SIGMAR1 (0.55) | SIGMAR1SMN1; SMN2IDO1POLB | |
| SCHEMBL9063693 | 0.79 | SIGMAR1 (0.44) | SIGMAR1SMN1; SMN2POLB | |
| SCHEMBL13675824 | 0.79 | SIGMAR1 (0.44) | SIGMAR1SMN1; SMN2POLB | |
| SCHEMBL4171219 | 0.73 | ALDH1A1 (0.52) | SIGMAR1SMN1; SMN2IDO1POLB | |
| SCHEMBL1318063 | 0.73 | ALDH1A1 (0.52) | SIGMAR1SMN1; SMN2IDO1POLB | |
| SCHEMBL21755741 | 0.73 | SIGMAR1 (0.49) | SIGMAR1IDO1POLB | |
| SCHEMBL1848291 | 0.73 | ALDH1A1 (0.52) | SIGMAR1SMN1; SMN2IDO1POLB | |
| SCHEMBL6286622 | 0.72 | HTR2A (0.60) | HTR2ASIGMAR1CTSCIDO1 | |
| SCHEMBL8825996 | 0.72 | HTR2A (0.51) | HTR2ARAB9AMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362001-B1 | N-CYCLOALKYL BENZYLAMINES ALPHA,ALPHA DISUBSTITUTED, THE PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND THEIR SYNTHESIS INTERMEDIATES | JOUVEINAL S.A. (FR) | 1993-03-10 | — | — | EP | disclosed |
| EP-0361990-B1 | DISUBSTITUTED BENZYLAMINES, THE PROCESS FOR THEIR PREPARATION, THEIR USE AS DRUGS AND THEIR SYNTHESES INTERMEDIATES | JOUVEINAL S.A. (FR) | 1993-02-24 | — | — | EP | disclosed |
| US-5017723-A | Psychotropic Agents | JOUVEINAL S.A. (FR) | 1991-05-21 | — | — | US | disclosed |
| EP-0362001-A1 | N-cycloalkyl benzylamines alpha,alpha disubstituted, the process for their preparation, their use as drugs and their synthesis intermediates | JOUVEINAL S.A. (FR) | 1990-04-04 | — | — | EP | disclosed |
| EP-0361990-A1 | Disubstituted benzylamines, the process for their preparation, their use as drugs and their syntheses intermediates | JOUVEINAL S.A. (FR) | 1990-04-04 | — | — | EP | disclosed |