Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | CTSB | P07858 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10649612 | 0.81 | CYP4F2 (0.48) | TDP1CTSBALDH1A1PKMKDM4E | |
| SCHEMBL9264908 | 0.76 | TDP1 (0.51) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9274567 | 0.75 | TDP1 (0.50) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL6519756 | 0.73 | ALDH1A1 (0.38) | TDP1CTSBALDH1A1PKMKDM4E | |
| SCHEMBL13430836 | 0.72 | TDP1 (1.00) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL2915235 | 0.70 | RARG (0.34) | TDP1ALDH1A1POLBKDM4ENOTUM | |
| SCHEMBL5382261 | 0.70 | TDP1 (0.50) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL9706679 | 0.69 | TDP1 (0.65) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| SCHEMBL3045754 | 0.69 | ALDH1A1 (0.73) | TDP1CTSBALDH1A1L3MBTL1POLB | |
| Urea SCHEMBL27809446 | 0.69 | GSK3A (0.46) | ALDH1A1RECQLMAPTNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017211-A | Herbicides | CIBA-GEIGY CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0333791-A1 | HETEROCYCLIC COMPOUNDS | CIBA-GEIGY AG (CH) | 1989-09-27 | — | — | EP | disclosed |
| WO-1989002891-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-04-06 | — | — | WO | disclosed |