Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19503752 | 0.78 | HTT (0.46) | HTTUSP2POLBTSHRHPGD | |
| SCHEMBL9878825 | 0.78 | HTT (0.70) | HTTLMNAHPGDGFERKDM4E | |
| SCHEMBL8515731 | 0.76 | KDM4E (0.60) | HTTLMNATSHRHPGDKDM4E | |
| SCHEMBL6025272 | 0.75 | HTT (0.56) | HTTLMNAHPGDGFERL3MBTL1 | |
| SCHEMBL9879120 | 0.74 | HTT (0.63) | HTTLMNATSHRHPGDGFER | |
| SCHEMBL9879081 | 0.72 | HTT (0.49) | HTTLMNAKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL31087177 | 0.71 | ALDH1A1 (0.65) | HTTLMNATSHRKDM4EL3MBTL1 | |
| SCHEMBL6025430 | 0.70 | LMNA (0.62) | HTTLMNAHPGDGFERL3MBTL1 | |
| SCHEMBL13932156 | 0.69 | HTT (0.56) | HTTLMNAPOLBHPGDGFER | |
| SCHEMBL9879418 | 0.69 | HTT (0.45) | HTTTSHRKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018887-A1 | DIAMINOPYRIMIDINE COMPOUNDS | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1991-12-12 | — | — | WO | disclosed |