Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869102 | 0.80 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27976332 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL7047557 | 0.75 | KDM4E (0.58) | KDM4EMAPTTDP1MMP2TSHR | |
| SCHEMBL17199419 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27836650 | 0.75 | LMNA (0.52) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22073007 | 0.75 | MMP2 (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL22072300 | 0.75 | LMNA (0.49) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL15451691 | 0.73 | TSHR (0.44) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL15381492 | 0.72 | LMNA (0.50) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL27742273 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991013874-A1 | DERIVATIVES OF GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1991-09-19 | — | — | WO | disclosed |