Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869102 | 0.78 | KDM4E (0.54) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL15451691 | 0.75 | TSHR (0.44) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL9879277 | 0.75 | KDM4E (0.46) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL7047557 | 0.74 | KDM4E (0.58) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL17199419 | 0.74 | KDM4E (0.48) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL22072300 | 0.73 | LMNA (0.49) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL27836650 | 0.73 | LMNA (0.52) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL9465327 | 0.72 | PARP1 (0.43) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL28477197 | 0.72 | TSHR (0.81) | MMP2TSHRCHRM1COMTADRA1A | |
| SCHEMBL17541529 | 0.72 | MMP2 (0.52) | MMP2TSHRCHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020114025-A1 | PREPARATION METHOD FOR β-LACTAM DERIVATIVES | 苏州大学 | 2020-06-11 | — | — | WO | disclosed |