Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CCR1 | P32246 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 3/20 | 0.54 |
| ▸ | CCR8 | P51685 | 3/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7047557 | 0.83 | KDM4E (0.58) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL17199419 | 0.82 | KDM4E (0.48) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL9879277 | 0.80 | KDM4E (0.46) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL27976332 | 0.80 | KDM4E (0.45) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL15381492 | 0.80 | LMNA (0.50) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL24113680 | 0.79 | LMNA (0.59) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL13021651 | 0.79 | KDM4E (0.54) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL9184043 | 0.79 | MAPT (0.50) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL22073007 | 0.78 | MMP2 (0.46) | KDM4EMAPTLMNACCR1CCR5 | |
| SCHEMBL22072300 | 0.78 | LMNA (0.49) | KDM4EMAPTLMNACCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005191-A1 | NITROGEN-CONTAINING COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS CONTAINING SAME | 陕西莱特光电材料股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2023001061-A1 | CDK7 SELECTIVE INHIBITORS AS ANTICANCER AGENTS | JINGRUI BIOPHARMA CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |
| US-11532790-B2 | Composition and light emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-12-20 | — | — | US | disclosed |
| CN-113474044-A | Bicyclic derivatives | 瑞士伊兰科动物保健有限公司 | 2021-10-01 | — | — | CN | disclosed |
| WO-2021135182-A1 | NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS | 陕西莱特光电材料股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| EP-3235891-B1 | COMPOSITION AND LIGHT-EMITTING ELEMENT USING SAME | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-20200194695-A1 | COMPOSITION, PHOSPHORESCENT COMPOUND, AND LIGHT EMITTING DEVICE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-06-18 | — | — | US | disclosed |
| WO-2020114025-A1 | PREPARATION METHOD FOR β-LACTAM DERIVATIVES | 苏州大学 | 2020-06-11 | — | — | WO | disclosed |
| US-20200044156-A1 | COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-02-06 | — | — | US | disclosed |
| US-9974782-B2 | Phosphodiesterase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-05-22 | — | — | US | disclosed |
| EP-2379076-B1 | PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | UNIV COLUMBIA (US) | 2014-11-12 | — | — | EP | disclosed |
| US-8697875-B2 | Phosphodiesterase inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-04-15 | — | — | US | disclosed |
| US-20120076732-A1 | PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-03-29 | — | — | US | disclosed |
| EP-2379076-A1 | PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | The Trustees of Columbia University in the City of New York (US) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010074783-A1 | PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2010-07-01 | — | — | WO | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200044156-A1 | COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME | CRY1, CRY2, EXOC1 | KDM4E 3472/4885MAPT 1997/4885LMNA 2731/4885 |
| US-20200194695-A1 | COMPOSITION, PHOSPHORESCENT COMPOUND, AND LIGHT EMITTING DEVICE | CRY1, C5, C1S | KDM4E 4796/4885MAPT 1713/4885LMNA 1832/4885 |
| US-11532790-B2 | Composition and light emitting device using the same | CRY1, CRY2, EXOC1 | KDM4E 3472/4885MAPT 1997/4885LMNA 2731/4885 |
| US-20120076732-A1 | PHOSPHODIESTERASE INHIBITORS AND USES THEREOF | PDE7A, PDE5A, PDE4A | KDM4E 1362/4885MAPT 1282/4885LMNA 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.