Styrene

Styrene

SCHEMBL9879339

C=C(CCC)C(=O)O.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
TSHR P16473 1/20 0.47
LMNA P02545 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
AKR1C3 P42330 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HDAC3 O15379 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALOX5 P09917 1/20 0.37
TP53 P04637 1/20 0.37
PTGS2 P35354 1/20 0.36
NPC1 O15118 2/20 0.36
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL1628104 0.97 ALDH1A1 (0.50) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL7043418 0.91 ALDH1A1 (0.39) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL294651 0.88 ALDH1A1 (0.48) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL8332408 0.88 ALDH1A1 (0.41) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL7619292 0.88 TDP1 (0.52) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL5270544 0.87 LMNA (0.47) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL17065130 0.87 LMNA (0.47) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL258132 0.87 LMNA (0.47) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL1628229 0.85 LMNA (0.54) ALDH1A1TSHRLMNATDP1CES2
Styrene SCHEMBL4407755 0.84 LMNA (0.43) ALDH1A1TSHRLMNATDP1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066707-A COMPOSITION GENERAL ELECTRIC COMPANY (US) 1991-11-19 US disclosed