Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838119 | 0.84 | POLB (0.67) | KMT2ALMNAHTTALDH1A1MEN1 | |
| SCHEMBL9870409 | 0.76 | GPR84 (0.47) | KMT2ALMNAALDH1A1GAAHPGD | |
| SCHEMBL17548428 | 0.75 | ACMSD (0.71) | KMT2ALMNAHTTALDH1A1ACMSD | |
| SCHEMBL9678318 | 0.74 | SMN1; SMN2 (0.47) | KMT2ALMNAALDH1A1MEN1HPGD | |
| SCHEMBL10699252 | 0.74 | SMN1; SMN2 (0.47) | KMT2ALMNAHTTALDH1A1MEN1 | |
| SCHEMBL26039905 | 0.73 | ALDH1A1 (0.70) | KMT2ALMNAHTTALDH1A1GAA | |
| SCHEMBL9879361 | 0.73 | MGAM (0.44) | KMT2ALMNAALDH1A1MEN1GAA | |
| SCHEMBL6483534 | 0.72 | RAB9A (0.64) | KMT2ALMNAHTTALDH1A1MEN1 | |
| SCHEMBL17068765 | 0.72 | HDAC1 (0.64) | KMT2ALMNAHTTALDH1A1ACMSD | |
| SCHEMBL9870574 | 0.71 | GLA (0.61) | KMT2ALMNAHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037830-A | Antisecretory-antiulcer agents | RICHTER GEDEON VEGYESZETI GYAR RT (HU) | 1991-08-06 | — | — | US | disclosed |
| EP-0391254-A2 | Novel thiouracil derivatives pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-10-10 | — | — | EP | disclosed |