Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11770393 | 0.81 | ALOX15 (0.37) | DAOCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL1612114 | 0.78 | CHRNB4 (0.40) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL7635136 | 0.75 | MCL1 (0.46) | MEN1KMT2AALDH1A1CASP1CASP7 | |
| SCHEMBL24924714 | 0.75 | HTT (0.39) | MEN1KMT2AALDH1A1ESR1PKM | |
| SCHEMBL24253522 | 0.75 | LMNA (0.44) | ALDH1A1CASP1CASP7HPGDPKM | |
| SCHEMBL24924883 | 0.75 | DAO (0.31) | DAOMEN1KMT2AHPGDMAPT | |
| SCHEMBL29849306 | 0.74 | CHRNB4 (0.39) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL14128913 | 0.73 | PDGFRB (0.38) | EGFRPDGFRBPDGFRADAOMEN1 | |
| SCHEMBL16878764 | 0.72 | MYC (0.56) | EGFRMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9979780 | 0.72 | MAPT (0.46) | EGFRPDGFRBPDGFRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037983-A | 6,7-dihydroxyquinoxalines as intermediates to beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | disclosed |