Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | FHIT | P49789 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879581 | 0.88 | GAA (0.49) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL9873241 | 0.83 | ALDH1A1 (0.41) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9871154 | 0.80 | ALDH1A1 (0.47) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL9872530 | 0.78 | ALDH1A1 (0.35) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9425038 | 0.77 | MAPT (0.37) | MAPTGAATDP1MEN1KMT2A | |
| Carbromal SCHEMBL9873682 | 0.72 | — | — | |
| SCHEMBL9319284 | 0.71 | KEAP1 (0.50) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL2271379 | 0.70 | ALDH1A1 (0.45) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5709551 | 0.69 | MAPT (0.57) | MAPTGAATDP1MEN1KMT2A | |
| SCHEMBL8571221 | 0.68 | ALDH1A1 (0.58) | MAPTGAATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037983-A | 6,7-dihydroxyquinoxalines as intermediates to beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4904775-A | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1990-02-27 | — | — | US | disclosed |