⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9873241 | 0.77 | ALDH1A1 (0.41) | — | |
| Carbromal SCHEMBL8832459 | 0.75 | POLB (0.32) | — | |
| Carbromal SCHEMBL6249616 | 0.72 | CRBN (0.37) | — | |
| SCHEMBL9879478 | 0.72 | MAPT (0.45) | — | |
| SCHEMBL9879581 | 0.72 | GAA (0.49) | — | |
| Carbromal SCHEMBL9726293 | 0.71 | KDM4E (0.55) | — | |
| Carbromal SCHEMBL5178580 | 0.71 | CRBN (0.36) | — | |
| Carbromal SCHEMBL8536554 | 0.71 | CRBN (0.36) | — | |
| Carbromal SCHEMBL4351621 | 0.71 | CRBN (0.39) | — | |
| Carbromal SCHEMBL15057476 | 0.71 | CRBN (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037983-A | 6,7-dihydroxyquinoxalines as intermediates to beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4904775-A | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0303286-A1 | 2-Oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E.R. Squibb & Sons, Inc. (US) | 1989-02-15 | — | — | EP | disclosed |