Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13144569 | 0.94 | ALDH1A1 (0.41) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL7618800 | 0.91 | GAA (0.50) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL13010591 | 0.84 | GAA (0.44) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL17126889 | 0.84 | KDM4E (0.37) | ALDH1A1GAATSHRKDM4EACHE | |
| SCHEMBL423443 | 0.82 | ACHE (0.47) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL12439226 | 0.81 | — | — | |
| SCHEMBL11658011 | 0.79 | GAA (0.41) | ALDH1A1LMNAHSD17B10GAAMGAM | |
| SCHEMBL10079787 | 0.78 | ACHE (0.35) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL13686222 | 0.78 | EPHX1 (0.35) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL13144619 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1LMNAHSD17B10GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9139552-B2 | Indeno-fused naphthopyrans having ethylenically unsaturated groups | TRANSITIONS OPTICAL, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | TRANSITIONS OPTICAL INC. (US) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120132870-A1 | Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups | ACR, INTS6, B3GNT2 | ALDH1A1 318/4885LMNA 312/4885HSD17B10 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.