SCHEMBL9880230

SCHEMBL9880230

C=C(C)C(=O)OCCOC(=O)CCC(=O)N1CCN(c2ccc(C3(c4ccccc4)C=Cc4c5c(c6cc(N7CCCCC7)c(OC)cc6c4O3)-c3ccccc3C5(C)C)cc2)CC1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 2/20 0.30
KMT2A Q03164 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9880233 0.94 L3MBTL1 (0.31) L3MBTL1
SCHEMBL16675440 0.93 MAPT (0.30) MAPT
SCHEMBL23623692 0.91
SCHEMBL2237768 0.89 L3MBTL1 (0.40) L3MBTL1MEN1KMT2AMAPT
SCHEMBL29453305 0.86 DRD2 (0.34) L3MBTL1
SCHEMBL1042878 0.86 DRD2 (0.34) L3MBTL1
SCHEMBL9882509 0.85 HTR1A (0.32)
SCHEMBL3243028 0.85
SCHEMBL1042903 0.84
SCHEMBL29453308 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11789291-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-10-17 US disclosed
US-11789291-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-10-17 US disclosed
US-20230296807-A1 CONTACT LENSES CONTAINING LIGHT ABSORBING REGIONS AND METHODS FOR THEIR PREPARATION JOHNSON & JOHNSON VISION CARE, INC. 2023-09-21 US disclosed
US-20230296807-A1 CONTACT LENSES CONTAINING LIGHT ABSORBING REGIONS AND METHODS FOR THEIR PREPARATION JOHNSON & JOHNSON VISION CARE, INC. 2023-09-21 US disclosed
US-20230286232-A1 METHODS FOR THE MANUFACTURE OF PHOTOABSORBING CONTACT LENSES AND PHOTOABSORBING CONTACT LENSES PRODUCED THEREBY JOHNSON & JOHNSON VISION CARE (US) 2023-09-14 US disclosed
US-20230286232-A1 METHODS FOR THE MANUFACTURE OF PHOTOABSORBING CONTACT LENSES AND PHOTOABSORBING CONTACT LENSES PRODUCED THEREBY JOHNSON & JOHNSON VISION CARE (US) 2023-09-14 US disclosed
US-11724471-B2 Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-11724471-B2 Methods for the manufacture of photoabsorbing contact lenses and photoabsorbing contact lenses produced thereby JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-11724472-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-11724472-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2023-08-15 US disclosed
US-9904074-B2 Pupil-only photochromic contact lenses displaying desirable optics and comfort JOHNSON & JOHNSON VISION CARE, INC. (US) 2018-02-27 US disclosed
US-9139552-B2 Indeno-fused naphthopyrans having ethylenically unsaturated groups TRANSITIONS OPTICAL, INC. (US) 2015-09-22 US disclosed
US-9139552-B2 Indeno-fused naphthopyrans having ethylenically unsaturated groups TRANSITIONS OPTICAL, INC. (US) 2015-09-22 US disclosed
US-8877103-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-11-04 US disclosed
US-8877103-B2 Process for manufacture of a thermochromic contact lens material JOHNSON & JOHNSON VISION CARE, INC. (US) 2014-11-04 US disclosed
WO-2013090220-A1 INDENO-FUSED NAPHTHOPYRANS HAVING ETHYLENICALLY UNSATURATED GROUPS PPG INDUSTRIES, INC. (US) 2013-06-20 WO disclosed
US-20120132870-A1 Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups TRANSITIONS OPTICAL INC. (US) 2012-05-31 US disclosed
US-20120132870-A1 Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups TRANSITIONS OPTICAL INC. (US) 2012-05-31 US disclosed
US-20110248415-A1 PROCESS FOR MANUFACTURE OF A THERMOCHROMIC CONTACT LENS MATERIAL JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed
US-20110248415-A1 PROCESS FOR MANUFACTURE OF A THERMOCHROMIC CONTACT LENS MATERIAL JOHNSON & JOHNSON VISION CARE, INC. 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120132870-A1 Indeno-Fused Naphthopyrans Having Ethylenically Unsaturated Groups ACR, INTS6, B3GNT2 L3MBTL1 4041/4885MEN1 3787/4885KMT2A 4609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.