Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 6/20 | 0.51 |
| ▸ | GABBR1 | Q9UBS5 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21610467 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL3637898 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL18854621 | 0.82 | MEN1 (0.47) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL24878696 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL3642655 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL24878661 | 0.82 | GABBR2 (0.53) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL10507284 | 0.81 | GABBR2 (0.64) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL3665299 | 0.81 | GABBR2 (0.51) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| Hydrochloric Acid SCHEMBL10681987 | 0.79 | GABBR2 (0.62) | GABBR2GABBR1LMNACYP2C9CYP1A2 | |
| SCHEMBL7669749 | 0.78 | GABBR2 (0.58) | GABBR2GABBR1LMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135984-A1 | DUAL-ACTION INHBITORS AND METHODS OF USING SAME | AERIE PHARMACEUTICALS, INC. | 2012-05-31 | — | — | US | disclosed |
| US-20120046272-A1 | Novel Therapeutic Compounds | GRUNENTHAL GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046272-A1 | Novel Therapeutic Compounds | GRUNENTHAL GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046272-A1 | Novel Therapeutic Compounds | OPRL1, OPRK1, OPRM1 | GABBR2 1598/4885GABBR1 1305/4885LMNA 3652/4885 |
| US-20120135984-A1 | DUAL-ACTION INHBITORS AND METHODS OF USING SAME | SLC6A2, ROCK2, SLC6A4 | GABBR2 1591/4885GABBR1 1094/4885LMNA 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.