Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9889090 | 0.87 | PTGER1 (0.57) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889103 | 0.84 | PTGER1 (0.50) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889129 | 0.83 | PTGER1 (0.49) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889119 | 0.80 | LTA4H (0.48) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL31587948 | 0.77 | MTNR1A (0.45) | PTGER1PTGER4PTGER3PTGER2FFAR4 | |
| SCHEMBL9889146 | 0.74 | CCR5 (0.41) | PTGER1PTGER4PTGER3PTGER2CYP2C9 | |
| SCHEMBL4891941 | 0.71 | FFAR4 (0.47) | PTGER1FFAR4CYP2C9APPFFAR1 | |
| SCHEMBL19511414 | 0.70 | CYP4F2 (0.46) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL15056556 | 0.70 | GLRA1 (0.45) | FFAR4CYP2C9FFAR1MTNR1AMTNR1B | |
| SCHEMBL5947113 | 0.69 | FFAR1 (0.66) | FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150369816-A1 | Polypeptide Immobilization | UNIV CHICAGO (US) | 2015-12-24 | — | — | US | disclosed |
| US-9074300-B2 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO (US) | 2015-07-07 | — | — | US | disclosed |
| US-20120142547-A1 | POLYPEPTIDE IMMOBILIZATION | THE UNIVERSITY OF CHICAGO | 2012-06-07 | — | — | US | disclosed |
| US-7888055-B2 | Selectively binds with absolute control over orientation and density without requiring prior synthetic modification or purification to make a stable protein chip; rapid and irreversible; assaying kinase or protease activity | THE UNIVERSITY OF CHICAGO (US) | 2011-02-15 | — | — | US | disclosed |
| US-20080064606-A1 | Polypeptide immobilization | THE UNIVERSITY OF CHICAGO | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064606-A1 | Polypeptide immobilization | QPCTL, SURF4, QPCT | PTGER1 4619/4885PTGER4 4340/4885PTGER3 4650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.