SCHEMBL9889357

SCHEMBL9889357

N=C(NP(=O)(O)O)N1CCC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
F2 P00734 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9889358 0.95 MMP1 (0.41) MMP1MMP2MMP3MMP9F2
SCHEMBL24116790 0.67 HPGD (0.37) ALDH1A1
Phosphoric Acid SCHEMBL17022775 0.67 F2 (0.45) MMP1MMP2MMP3MMP9F2
SCHEMBL24116789 0.66
SCHEMBL14595297 0.65
SCHEMBL15588635 0.64 F2 (0.46) F2ALDH1A1
SCHEMBL15588798 0.62 F2 (0.50) MMP1MMP2MMP3MMP9F2
SCHEMBL15588799 0.62 F2 (0.50) MMP1MMP2MMP3MMP9F2
Hydrochloric Acid SCHEMBL15560657 0.62 F2 (0.43) F2ALDH1A1
SCHEMBL4586883 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION WASHINGTON UNIVERSITY 2023-09-14 US disclosed
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF GENCIA CORPORATION (US) 2014-02-13 US disclosed
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof GENCIA CORPORATION (US) 2013-03-21 US disclosed
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation AVICENA GROUP, INC. (US) 2012-06-07 US disclosed
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-04-14 US disclosed
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2011-01-27 US disclosed
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation AVICENA GROUP, INC. (US) 2011-01-13 US disclosed
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION AVICENA GROUP, INC. (US) 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140045798-A1 MITOCHONDRIAL COMPOSITIONS AND USES THEREOF CS, UQCRC1, UQCRC2 MMP1 1967/4885MMP2 1876/4885MMP3 2162/4885
US-20110008272-A1 Use of Creatine or Creatine Compounds for Skin Preservation PC, CKMT1A; CKMT1B, CHEK1 MMP1 1796/4885MMP2 1970/4885MMP3 862/4885
US-20120141391-A1 Use of creatine or creatine compounds for skin preservation PC, CKMT1A; CKMT1B, CHEK1 MMP1 1796/4885MMP2 1970/4885MMP3 862/4885
US-20100329997-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 MMP1 1796/4885MMP2 1970/4885MMP3 862/4885
US-20110021632-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 MMP1 1796/4885MMP2 1970/4885MMP3 862/4885
US-20110085993-A1 USE OF CREATINE OR CREATINE COMPOUNDS FOR SKIN PRESERVATION PC, CKMT1A; CKMT1B, CHEK1 MMP1 1796/4885MMP2 1970/4885MMP3 862/4885
US-20230285338-A9 METHODS FOR TREATING MICROGLIAL DYSFUNCTION CX3CR1, CD68, FYN MMP1 1789/4885MMP2 2247/4885MMP3 1492/4885
US-20130072462-A1 Mitochondrial Compositions and Uses Thereof UQCRC1, CS, UQCRC2 MMP1 2274/4885MMP2 2078/4885MMP3 2073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.