Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.54 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101169 | 0.88 | ALDH1A1 (0.53) | ALDH1A1TDP1CSNK2A1PTGESLOXL2 | |
| SCHEMBL3905288 | 0.85 | ALDH1A1 (0.58) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL3904427 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1CSNK2A1PTGESCRHBP | |
| SCHEMBL15860172 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL9590489 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL279052 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL98747 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL15822786 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1PTGESCRHBPCRHR2 | |
| SCHEMBL8701556 | 0.80 | ALDH1A1 (0.65) | ALDH1A1TDP1LOXL2TAAR1TSHR | |
| SCHEMBL27559990 | 0.79 | FFAR1 (0.53) | ALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9072734-B2 | Quaternary ammonium salt compounds | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | TEIJIN PHARMA LIMITED (JP) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046467-A1 | QUATERNARY AMMONIUM SALT COMPOUNDS | ADRB2, AGTR2, ADRB3 | ALDH1A1 1896/4885TDP1 4429/4885CSNK2A1 337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.