Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17427772 | 0.90 | PLK1 (0.44) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL24430171 | 0.87 | NPC1 (0.45) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL8496037 | 0.86 | S1PR1 (0.52) | S1PR1ALDH1A1KDM4ETAAR1NPC1 | |
| SCHEMBL588956 | 0.86 | POLB (0.42) | S1PR1KDM4EACACBTAAR1NPC1 | |
| SCHEMBL15958710 | 0.85 | ALDH1A1 (0.46) | ALDH1A1KDM4ETAAR1NPC1RAB9A | |
| SCHEMBL8499619 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL8496762 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL903624 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL8501555 | 0.85 | S1PR1 (0.60) | S1PR1S1PR3TNNC1SGPL1S1PR4 | |
| SCHEMBL12064836 | 0.83 | TNNC1 (0.43) | S1PR1S1PR3TNNC1SGPL1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120141513-A1 | DEUTERATED FINGOLIMOD | CONCERT PHARMACEUTICALS INC. | 2012-06-07 | — | — | US | disclosed |
| US-20090176744-A1 | Deuterated fingolimod | CONCERT PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120141513-A1 | DEUTERATED FINGOLIMOD | S1PR1, S1PR3, S1PR4 | S1PR1 1/4885S1PR3 2/4885TNNC1 4402/4885 |
| US-20090176744-A1 | Deuterated fingolimod | S1PR1, S1PR3, S1PR4 | S1PR1 1/4885S1PR3 2/4885TNNC1 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.