Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 8/20 | 0.60 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.60 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.60 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.60 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.60 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499619 | 1.00 | S1PR1 (0.60) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL8496762 | 1.00 | S1PR1 (0.60) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL8501555 | 1.00 | S1PR1 (0.60) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL16919264 | 0.90 | S1PR1 (0.52) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL17427772 | 0.88 | PLK1 (0.44) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL18630036 | 0.87 | S1PR1 (0.55) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL15796686 | 0.87 | S1PR1 (0.46) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL18618719 | 0.87 | S1PR1 (0.55) | S1PR1S1PR4S1PR3TNNC1S1PR5 | |
| SCHEMBL8496714 | 0.87 | S1PR1 (0.56) | S1PR1S1PR4S1PR3S1PR5 | |
| SCHEMBL12064836 | 0.87 | TNNC1 (0.43) | S1PR1S1PR4S1PR3TNNC1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964210-B1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LTD (IN) | 2023-10-04 | — | — | EP | claimed |
| US-9815772-B2 | Process for the preparation of 2-amino-1,3-propane diol compounds and salts thereof | BIOCON LIMITED (IN) | 2017-11-14 | — | — | US | claimed |
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LIMITED (IN) | 2016-01-14 | — | — | US | claimed |
| EP-2964210-A2 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | Biocon Limited (IN) | 2016-01-13 | — | — | EP | claimed |
| US-20150290145-A1 | Compositions and Methods for the Treatment of Parkinson's Disease | TEXAS TECH UNIVERSITY SYSTEM | 2015-10-15 | — | — | US | claimed |
| WO-2014136047-A2 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LIMITED (IN) | 2014-09-12 | — | — | WO | claimed |
| WO-2014063057-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PARKINSON'S DISEASE | TEXAS TECH UNIVERSITY SYSTEM (US) | 2014-04-24 | — | — | WO | claimed |
| EP-2964210-B1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | BIOCON LTD (IN) | 2023-10-04 | — | — | EP | disclosed |
| US-10391066-B2 | Compositions and methods for the treatment of Parkinson's disease | TEXAS TECH UNIVERSITY SYSTEM (US) | 2019-08-27 | — | — | US | disclosed |
| US-10391066-B2 | Compositions and methods for the treatment of Parkinson's disease | TEXAS TECH UNIVERSITY SYSTEM (US) | 2019-08-27 | — | — | US | disclosed |
| EP-2896609-B1 | Crystalline fingolimod citrate for the treatment of relapsing-remitting multiple sclerosis | RATIOPHARM GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-9994638-B2 | Peptide core-based multi-arm linkers for treating infectious diseases | Immunwork Inc. (TW) | 2018-06-12 | — | — | US | disclosed |
| US-9988454-B2 | Peptide core-based multi-arm linkers for treating central nervous system diseases | Immunwork Inc. (TW) | 2018-06-05 | — | — | US | disclosed |
| US-7638637-B2 | Immunomodulators; amino-functional imidazole phosphonates and analogues thereof | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2009-12-29 | — | — | US | disclosed |
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-04-19 | — | — | US | disclosed |
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088002-A1 | Orally available sphingosine 1-phosphate receptor agonists and antagonists | S1PR3, S1PR1, S1PR5 | S1PR1 2/4885S1PR4 4/4885S1PR3 1/4885 |
| US-20160009634-A1 | A PROCESS FOR THE PREPARATION OF 2-AMINO-1,3-PROPANE DIOL COMPOUNDS AND SALTS THEREOF | ADH1C, DRD2, ADH1A | S1PR1 1162/4885S1PR4 1520/4885S1PR3 847/4885 |
| US-20150290145-A1 | Compositions and Methods for the Treatment of Parkinson's Disease | PARK7, SNCA, COMT | S1PR1 390/4885S1PR4 545/4885S1PR3 298/4885 |
| US-10391066-B2 | Compositions and methods for the treatment of Parkinson's disease | PARK7, SNCA, COMT | S1PR1 390/4885S1PR4 545/4885S1PR3 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.