SCHEMBL989137

SCHEMBL989137

O=[PH](Oc1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
LMNA P02545 2/20 0.36
CYP2A6 P11509 1/20 0.36
HPGD P15428 1/20 0.35
PPARA Q07869 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SOD1 P00441 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LIPE Q05469 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4408434 0.78 MEN1 (0.43) MEN1KMT2ACA1CA2CA9
SCHEMBL23777849 0.77 MEN1 (0.44) MEN1KMT2ACA1CA2CA9
SCHEMBL969753 0.77 ACHE (0.42) MEN1KMT2ACA1CA2CA9
SCHEMBL3191986 0.77 CA1 (0.50) CA1CA2CA9CYP2A6CYP3A4
SCHEMBL18037119 0.74 HPGD (0.41) MEN1KMT2ACA1CA2CA9
SCHEMBL11663727 0.74 LTA4H (0.50) CA1CA2CA9MAOALMNA
SCHEMBL28876962 0.72 NQO1 (0.56) MEN1KMT2ACA1CA2CA9
SCHEMBL988094 0.72 SMN1; SMN2 (0.42) KMT2ACA2LMNAHPGDPPARA
SCHEMBL4320820 0.72 CA1 (0.44) MEN1KMT2ACA1CA2CA9
SCHEMBL258694 0.71 LTA4H (0.39) KMT2ACA1CA2CA9MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369716-A A kind of aryl oxidized phosphine compound and its synthetic method and application 广东工业大学 2019-02-22 CN disclosed
US-9822425-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2017-11-21 US disclosed
US-8968698-B2 Processes for recovering metals from aqueous solutions CYTEC TECHNOLOGY CORP. (US) 2015-03-03 US disclosed
US-20140127095-A1 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2014-05-08 US disclosed
EP-2451985-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS Cytec Technology Corporation (US) 2012-05-16 EP disclosed
WO-2011005736-A2 PROCESSES FOR RECOVERING METALS FROM AQUEOUS SOLUTIONS CYTEC TECHNOLOGY CORP. (US) 2011-01-13 WO disclosed