SCHEMBL9891386

SCHEMBL9891386

CCC(O)COC(=O)C(C)CC

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
DUSP3 P51452 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
LMNA P02545 1/20 0.35
ADRB2 P07550 3/20 0.33
ADRB1 P08588 3/20 0.33
ADRB3 P13945 3/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
LPAR6 P43657 1/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR4 Q99677 1/20 0.31
LPAR5 Q9H1C0 1/20 0.31
LPAR2 Q9HBW0 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16946535 0.93 KDM4E (0.36) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL16942487 0.93 KDM4E (0.36) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL19428722 0.87 KDM4E (0.38) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL1640082 0.87 LMNA (0.49) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL25491976 0.87 KMT2A (0.33) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL19821873 0.85 KDM4E (0.33) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL19821867 0.85 TDP1 (0.41) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL25560265 0.85 ALDH1A1 (0.33) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL15512210 0.84 KDM4E (0.36) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL26950808 0.84 KDM4E (0.36) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773266-B2 Polymer, molded body, foam, resin composition, and production method for polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-03 US disclosed
US-20230129965-A1 HYDROPHILIC AND OLEOPHOBIC POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-04-27 US disclosed
US-20180030175-A1 POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-01 US disclosed
US-9558987-B2 Gap-fill methods DOW GLOBAL TECHNOLOGIES LLC (US) 2017-01-31 US disclosed
US-9324604-B2 Gap-fill methods ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2016-04-26 US disclosed
US-20160005641-A1 GAP-FILL METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-01-07 US disclosed
US-20150348828-A1 GAP-FILL METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2015-12-03 US disclosed
US-9044411-B2 Agent for keratinous fibers, comprising at least one acrylate/glyceryl acrylate copolymer, at least one film-forming and/or solidifying polymer and at least one ester oil HENKEL AG & CO. KGAA (DE) 2015-06-02 US disclosed
US-20140050686-A1 AGENT FOR KERATINOUS FIBERS, COMPRISING AT LEAST ONE ACRYLATE/GLYCERYL ACRYLATE COPOLYMER, AT LEAST ONE FILM-FORMING AND/OR SOLIDIFYING POLYMER AND AT LEAST ONE ESTER OIL HENKEL AG & CO. KGAA (DE) 2014-02-20 US disclosed
US-20130237471-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2013-09-12 US disclosed
US-20130237471-A1 POLYMERS, COMPOSITIONS AND METHODS OF USE FOR FOAMS, LAUNDRY DETERGENTS, SHOWER RINSES AND COAGULANTS RHODIA INC. (US) 2013-09-12 US disclosed
US-8492481-B2 Block polymers, compositions and methods for use for foams, laundry detergents, and shower rinses and coagulants RHODIA INC. (US) 2013-07-23 US disclosed
US-20120141406-A1 AGENT FOR KERATINOUS FIBERS, COMPRISING AT LEAST ONE ACRYLATE/GLYCERYL ACRYLATE COPOLYMER, AT LEAST ONE FILM-FORMING AND/OR SOLIDIFYING POLYMER AND AT LEAST ONE ESTER OIL HENKEL AG & CO. KGAA (DE) 2012-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140050686-A1 AGENT FOR KERATINOUS FIBERS, COMPRISING AT LEAST ONE ACRYLATE/GLYCERYL ACRYLATE COPOLYMER, AT LEAST ONE FILM-FORMING AND/OR SOLIDIFYING POLYMER AND AT LEAST ONE ESTER OIL KRT18, ACR, CUTA KDM4E 1667/4885DUSP3 3579/4885MEN1 1414/4885
US-20120141406-A1 AGENT FOR KERATINOUS FIBERS, COMPRISING AT LEAST ONE ACRYLATE/GLYCERYL ACRYLATE COPOLYMER, AT LEAST ONE FILM-FORMING AND/OR SOLIDIFYING POLYMER AND AT LEAST ONE ESTER OIL KRT18, ACR, CUTA KDM4E 1667/4885DUSP3 3579/4885MEN1 1414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.